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AAV Testing & Characterization 

Biochemical & Biophysical Assays

SKU#
Assay
Method
0101
pH
USP/EP
0102
Osmolarity
USP/EP
0103
Appearance
USP/EP
0104
Density
USP <841> Specific Gravity
0106
Aggregation
SEC-HPLC
0107
Aggregation
Dynamic Light Scattering
0108
Full/Empty Ratio
AAV genome titer vs AAV capsid titer
0111
Full/Empty Ratio
Transmission Electron Microscopy

Identity & Quantity

SKU#
Assay
Method
0202
Capsid Identity
SDS-PAGE Western Blot
0203
Transgene Identity
Agarose Denaturing Gel
0204
Transgene Identity
Sanger Sequencing
0205
ITR integrity
NGS
0206
Protein Gel
SDS-PAGE Silver Stain
0206A
Protein Gel
SDS-PAGE Coomassie Blue
0208
Vector Genome Titer
Digital Droplet PCR
0209
Vector Genome Titer
TaqMan qPCR
0210
Microtiter Plate
Micro-BCA Assay
0211
UV Spectroscope
Nanodrop Assay
0212
AAV Infectivity
TCID50 Assay
0213
AAV Genome Expression
ELISA
0214
Functional Vector Genome
Multiplex ddPCR
0215
Potency Assay
ELISA

Process Impurities

SKU#
Assay
Method
0301
Residual Sf9 Cell Protein
ELISA
0302
Residual Sf9 Cell DNA
Digital Droplet PCR
0303
Residual Sf9 cell DNA
TaqMan qPCR
0304
Residual Plasmid DNA
Digital Droplet PCR
0305
Leachable AAVx Antibody
ELISA
0306
Residual Benzonase
ELISA
0307
Triton X-100
RP-HPLC
0308
Iodixanol
SEC-HPLC
0309
Tween 20 Concentration
RP-HPLC-CAD

Viral Safety

SKU#
Assay
Method
0401
Residual Baculovirus Protein
ELISA
0402
Sf-rhabdovirus Titer
RT-ddPCR
0403
Sf-rhabdovirus Infectivity
Cell Based Assay
0404
Endotoxin
USP <85>, EP 2.6.14 LAL
0406
Replication Competent AAV
qPCR
0410
Replication Competent Baculovirus
28-day Assay

Get in Touch

25503 Whitesell St,

Hayward, CA 94545

1(510)397-2333

info@avirmax.com

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